There is a website dedicated to providing correct medical information in the United States called the American Council on Science and Health. It published Think Your Vitamin C is ‘Natural?’ Think Again (Do you think your vitamin C is "natural"? Think again).

The author of this article is Jose Bloom, PhD in Organic Chemistry. He is the director of chemistry and pharmaceutical science for this association.

The subtitle of this article is: Do you think vitamin C comes from hand-picked orange and sunlight? Or it is synthesized with corn sugar, sulfuric acid and genetically modified microorganisms. This is not a fairy tale. This is industrial chemistry with a thorny meaning.

Since Dr. Jose Bloom's articles are all made with the unique black humor and ridicule of English, it will be indefinitely translated into Chinese. So I had to do some adjustments so that Chinese readers can understand more clearly. Here is the adjusted translation:

90% of the vitamin C for U.S. consumption is produced in China. And it certainly didn't come from oranges.

Vitamin C synthesis was invented by Tadeusz Reichstein, a native of the Polish Polish in 1933, so this synthesis method is called The Reichstein process. Its steps are:

1. Use hydrogen and ozone catalyst to hydrate D-glucose into D-sorbitol under high temperature and pressure.

2. Use Acetobacter suboxydans to ·L-sorbate.

3. Transform L-sorbito into double acetone-L-sorbito using acidic catalyst and acetone.

4. Oxidize double acetone-L-sorbitan to ·2-one-L-guloconic acid.

5. Under acidic conditions or by heating, decorate 2-one-L-guloconate into anti-aging blood acid (i.e., vitamin C).

The Reichstein process has been made many improvements in the past 90 years, such as:

1. Use base-based corn to make corn flour.

2. Use α-powder enzyme produced by the base-modified yeast Saccharomyces cerevisiae to convert corn flour into D-glucose.

3. Use base-modification bacteria Ketogulonicigenium vulgare to convert L-sorbate into ·2-one-L-guloconic acid.

Moderator notes: Dr. Jose Bloom emphasizes "basic modification" because people who advocate "natural" cannot accept foods for basic modification. So, he mockedly said that the so-called "natural vitamin C" is not only synthesized, but also synthesized with basic modified yeasts and bacteria.